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Impact of stagnation and distribution on drinking water microbiota
Drinking water distribution plays a critical role in safeguarding public health, affecting the quality of the water than is delivered to consumers’ taps. While most studies investigated the impact of either distribution or stagnation on the prokaryotic (i.e., bacterial and archaeal) communities in drinking water, the relative importance of the two aspects has not been properly compared. In addition, very little information is available on non-prokaryotic microbiome members (i.e., viruses, eukaryotes), both with respect to their occurrence in drinking water and the extent to which they are impacted by stagnation and water distribution.
While amplicon sequencing approaches are limited by primer coverage and allow to recover only taxonomic information, shotgun metagenomics can overcome these limits, allowing to monitor the DNA derived from all microbiome members and gather information regarding both taxonomy and functional potential.
This project aims to leverage shotgun metagenomics to evaluate the impact of water distribution and stagnation on the entire microbiome composition.
The main tasks expected in the project will be to perform quality control and assembly of shotgun metagenomic data, to use several bioinformatic pipelines to characterize the drinking water microbiome and to apply statistical methods to assess the significance of the observed changes.
The main tasks expected in the project will be to perform quality control and assembly of shotgun metagenomic data, to use several bioinformatic pipelines to characterize the drinking water microbiome and to apply statistical methods to assess the significance of the observed changes.
The goal of this project is to leverage shotgun metagenomic data to assess the impact of drinking water distribution and stagnation on the taxonomic composition and relative abundance of drinking water microbiome.
The goal of this project is to leverage shotgun metagenomic data to assess the impact of drinking water distribution and stagnation on the taxonomic composition and relative abundance of drinking water microbiome.
Interested students are invited to apply for the Spring 2024 semester. For more information, please contact: Dr. Marco Gabrielli (marco.gabrielli@eawag.ch), Dr. Frederik Hammes (frederik.hammes@eawag.ch)
Interested students are invited to apply for the Spring 2024 semester. For more information, please contact: Dr. Marco Gabrielli (marco.gabrielli@eawag.ch), Dr. Frederik Hammes (frederik.hammes@eawag.ch)