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Hardware development for optical “PET”
FMT non-invasively resolves the three-dimensional distribution of fluorescent probes in vivo. Thus, it can be considered an optical version of PET (but only 1% cost of PET). A miniaturized FMT with compact design and easy handling is certainly attractive. This calls for the integration of MEMS.
Keywords: Medical imaging, hardware development, optical imaging, MEMS
Are you interested in medical imaging field? Are you curious about how to develop a 3D optical imaging device? Here you found the right place.
Fluorescence molecular tomography (FMT) provides molecular information on tracer bio-distribution in the organism similar to positron emission tomography (PET). Instead of using radioactive tracers in PET, FMT non-invasively resolves the three-dimensional distribution of fluorescent probes in vivo. Thus, it can be considered an optical version of PET (but only 1% cost of PET). Although both image reconstruction algorithms and instrumentation for FMT have evolved over the past decade, none of the setups has been widely accepted as a standard molecular imaging tool for routine biomedical research. A miniaturized FMT with compact design and easy handling is certainly attractive. This calls for the integration of a MEMS chip. The aim of the thesis is to integrate a MEMS chip into the current FMT design with stable power supply.
Previously we have developed a compact FMT/MRI hybrid system, which serves as a starting point for the project.
Students with background of electronic engineering, applied optics, and robotics are encouraged to apply!
The project has been received as 'BRIDGE proof-of-concept' project in 2017.
Are you interested in medical imaging field? Are you curious about how to develop a 3D optical imaging device? Here you found the right place.
Fluorescence molecular tomography (FMT) provides molecular information on tracer bio-distribution in the organism similar to positron emission tomography (PET). Instead of using radioactive tracers in PET, FMT non-invasively resolves the three-dimensional distribution of fluorescent probes in vivo. Thus, it can be considered an optical version of PET (but only 1% cost of PET). Although both image reconstruction algorithms and instrumentation for FMT have evolved over the past decade, none of the setups has been widely accepted as a standard molecular imaging tool for routine biomedical research. A miniaturized FMT with compact design and easy handling is certainly attractive. This calls for the integration of a MEMS chip. The aim of the thesis is to integrate a MEMS chip into the current FMT design with stable power supply.
Previously we have developed a compact FMT/MRI hybrid system, which serves as a starting point for the project.
Students with background of electronic engineering, applied optics, and robotics are encouraged to apply!
The project has been received as 'BRIDGE proof-of-concept' project in 2017.
1. Integration of a MEMS chip.
2. Installation of proper power supply.
3. Performance evaluation with silicone phantom.
1. Integration of a MEMS chip. 2. Installation of proper power supply. 3. Performance evaluation with silicone phantom.
Dr. Wuwei Ren
Email: ren@biomed.ee.ethz.ch
Phone: +41 44 633 76 52
Prof. Martin Wolf
Email: Martin.Wolf@usz.ch
Phone: +41 44 255 53 46
Prof. Markus Rudin
Email: rudin@biomed.ee.ethz.ch
Phone: +41 44 633 76 04
Each year the IDEA League offers the students of its partner universities over 180 monthly grants for a short-term research exchange. In general, these grants are awarded based on academic merit. For more information visit http://idealeague.org/student-grant/