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Optimize and Validate a Wireless Sensor System for In Vivo Measurement of Soft Tissue Strain on Sheep Model
Quantitative assessment of in vivo strain patterns of musculoskeletal soft tissues during dynamic activities is important to reveal tissue function and identify injury mechanisms. However, there is a clear lack of a reliable technique to assess in vivo strain patterns of soft tissues.
Quantitative assessment of in vivo strain patterns of musculoskeletal soft tissues during dynamic activities is important to reveal tissue function and identify injury mechanisms. However, there is a clear lack of a reliable technique to assess in vivo strain patterns of soft tissues.
Our research group has developed an implantable sensor system for real-time measurement of ligament and tendon strains by combining soft electronics and a wireless electronic readout device. This project therefore aims to optimize the wireless signal communication and system configuration to achieve measurements over a wider range of strains and to enable an in vivo implantation of the sensor in sheep. The goal is to optimize the current system to measure strains up to 30% with high precision and sensitivity. Furthermore, the readout system must also be improved to enable wireless transmission and data storage from multiple sensors attached to different soft tissues (e.g. quadriceps muscle and patellar tendon). Finally, the attachment of the readout system to the sheep body will be designed to easily mount the device on the sheep body without restricting natural movements. The main tasks of this project will include hardware optimization and system validation. Finally, a cadaveric experiment will be performed on sheep joint to demonstrate the wireless transmission capability of this sensor system.
Quantitative assessment of in vivo strain patterns of musculoskeletal soft tissues during dynamic activities is important to reveal tissue function and identify injury mechanisms. However, there is a clear lack of a reliable technique to assess in vivo strain patterns of soft tissues. Our research group has developed an implantable sensor system for real-time measurement of ligament and tendon strains by combining soft electronics and a wireless electronic readout device. This project therefore aims to optimize the wireless signal communication and system configuration to achieve measurements over a wider range of strains and to enable an in vivo implantation of the sensor in sheep. The goal is to optimize the current system to measure strains up to 30% with high precision and sensitivity. Furthermore, the readout system must also be improved to enable wireless transmission and data storage from multiple sensors attached to different soft tissues (e.g. quadriceps muscle and patellar tendon). Finally, the attachment of the readout system to the sheep body will be designed to easily mount the device on the sheep body without restricting natural movements. The main tasks of this project will include hardware optimization and system validation. Finally, a cadaveric experiment will be performed on sheep joint to demonstrate the wireless transmission capability of this sensor system.
This project aims to optimize the wireless signal communication and system configuration of our sensor system to achieve measurements over a wider range of strains and to enable an in vivo implantation of the sensor in sheep.
This project aims to optimize the wireless signal communication and system configuration of our sensor system to achieve measurements over a wider range of strains and to enable an in vivo implantation of the sensor in sheep.
Contact: Qiang Zhang (qiang.zhang@hest.ethz.ch), Institute for Biomechanics. Professorship William R. Taylor
Contact: Qiang Zhang (qiang.zhang@hest.ethz.ch), Institute for Biomechanics. Professorship William R. Taylor