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Bioimaging/Computational fluid dynamics (CFD) at ETH Zurich
The Institute for Biomechanics at ETH Zurich is offering a student project in the area of computational fluid dynamics (CFD). The applicant should be enrolled in an engineering study course or a related field. Knowledge in Bioimaging and especially in CFD is an advantage
Fluid flow has been hypothesized to be one of the main drivers for mechanobiological processes, which are crucial for bone homeostasis. On this account, we recently proposed a cell-based framework for nanoscopic bone imaging and computational fluid dynamics (CFD). In particular, we developed new techniques for 3D nanoscopic imaging of the lacuno-canalicular network (LCN), where the LCN encloses the network of bone cells called osteocytes, which form the mechanosensory organ of bone tissue. These new nanoscopic imaging techniques already provided data sets of the LCN within bone tissue of mice and men of different age. Based on these data sets, our goal is to investigate the influence of species and age on mechanotransduction via fluid dynamics within the LCN.
Therefore, the current project focuses on CFD simulation based on 3D microstructural images of the LCN.
Contact: Dr. Philipp Schneider, pschneider@ethz.ch / Institute for Biomechanics, HCI E 365.1, ETH Zürich / Professorship Ralph Müller
Fluid flow has been hypothesized to be one of the main drivers for mechanobiological processes, which are crucial for bone homeostasis. On this account, we recently proposed a cell-based framework for nanoscopic bone imaging and computational fluid dynamics (CFD). In particular, we developed new techniques for 3D nanoscopic imaging of the lacuno-canalicular network (LCN), where the LCN encloses the network of bone cells called osteocytes, which form the mechanosensory organ of bone tissue. These new nanoscopic imaging techniques already provided data sets of the LCN within bone tissue of mice and men of different age. Based on these data sets, our goal is to investigate the influence of species and age on mechanotransduction via fluid dynamics within the LCN.
Therefore, the current project focuses on CFD simulation based on 3D microstructural images of the LCN.
Contact: Dr. Philipp Schneider, pschneider@ethz.ch / Institute for Biomechanics, HCI E 365.1, ETH Zürich / Professorship Ralph Müller
Not specified
Dr. Philipp Schneider
Institute for Biomechanics
ETH Zurich, Wolfgang-Pauli-Strasse 10, 8093 Zurich, Switzerland
Email: pschneider@ethz.ch
Web: http://www.biomech.ethz.ch/
Dr. Philipp Schneider Institute for Biomechanics ETH Zurich, Wolfgang-Pauli-Strasse 10, 8093 Zurich, Switzerland Email: pschneider@ethz.ch Web: http://www.biomech.ethz.ch/